RA Capital Management, L.P. Insider Trading Activity

Institutional Filer10%+ Owner · CIK 1346824

138

Total trades

$617.1M

Total volume

May 20, 2026

Last activity

SION

Sionna Therapeutics, Inc.

RA Capital Management, L.P., an institutional filer, recorded 136 transactions over the last 12 months across 16 companies totaling $605.3M.

Activity concentrated in SION with 44 filings. The largest single transaction was a purchase of CDTX for $100.0M on Jun 26, 2025.

Performance Scorecard

Forward stock performance after each transaction by RA Capital Management, L.P.. Buy returns measure price movement after open-market purchases; sell-avoided measures the loss avoided after open-market sales. Success rate counts trades where the insider's direction was right.

PERIODAVG BUY RETURNAVG SELL AVOIDEDSUCCESS RATETRADES
30 days+28.0%+20.6%57%123
90 days+52.8%+22.0%92%96
120 days+90.1%+27.9%100%90

Performance based on stock price movement after each transaction date. Past results do not predict future returns. Not financial advice.

Price & Trades

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Recent Trades

Showing the 50 most recent of 138 disclosed trades.

DATETICKERTYPESHARESPRICEVALUEROLE
May 20, 2026COAGBuy996$24.94$25K10%+ Owner
May 19, 2026COAGBuy3,802$24.97$95K10%+ Owner
May 12, 2026HOWLSell94,432$0.64$60K10%+ Owner
May 12, 2026HOWLSell6,719$0.64$4K10%+ Owner
May 12, 2026COAGBuy6,387$24.90$159K10%+ Owner
May 11, 2026COAGBuy14,149$24.47$346K10%+ Owner
May 11, 2026HOWLSell5,812$0.67$4K10%+ Owner
May 11, 2026COAGBuy25,720$25.00$643K10%+ Owner
May 11, 2026HOWLSell81,678$0.67$55K10%+ Owner
May 11, 2026ARTVBuy6,510,416$11.52$75.0MDirector
May 8, 2026COAGBuy1,483$24.98$37K10%+ Owner
May 8, 2026HOWLSell25,012$0.71$18K10%+ Owner
May 8, 2026HOWLSell351,514$0.71$250K10%+ Owner
May 7, 2026COAGBuy1,985$24.95$50K10%+ Owner
May 7, 2026COAGBuy7,921$24.34$193K10%+ Owner
May 6, 2026COAGBuy14,611$23.77$347KDirector
May 6, 2026COAGBuy53,407$24.83$1.3MDirector
May 5, 2026COAGBuy10,268$25.00$257KDirector
May 5, 2026COAGBuy87,143$24.59$2.1MDirector
May 4, 2026COAGBuy133,750$18.00$2.4MDirector
May 4, 2026COAGBuy2,541,250$18.00$45.7MDirector
Apr 22, 2026VORSell165,150$15.77$2.6MDirector
Apr 20, 2026VORSell171,963$15.77$2.7MDirector
Apr 17, 2026VORSell458,411$16.28$7.5MDirector
Apr 15, 2026VORSell53,644$16.01$859KDirector
Apr 14, 2026VORSell153,735$15.97$2.5MDirector
Apr 13, 2026VORSell530,610$16.15$8.6MDirector
Apr 10, 2026VORSell828$15.75$13KDirector
Apr 9, 2026VORSell135,201$16.59$2.2MDirector
Apr 8, 2026VORSell353,242$16.32$5.8MDirector
Apr 8, 2026VORSell130,862$16.91$2.2MDirector
Apr 6, 2026VORSell6,775$18.50$125KDirector
Apr 6, 2026VORSell44,728$17.31$774KDirector
Apr 6, 2026VORSell537,754$16.51$8.9MDirector
Apr 2, 2026VORSell258,475$18.23$4.7MDirector
Apr 2, 2026VORSell1,525$19.06$29KDirector
Mar 30, 2026WVEBuy971,091$6.50$6.3MDirector
Mar 30, 2026MLYSBuy58,300$24.16$1.4MDirector
Mar 27, 2026WVEBuy2,495,623$6.43$16.0MDirector
Mar 27, 2026MLYSBuy310,700$23.67$7.4MDirector
Mar 26, 2026WVEBuy351,224$6.38$2.2MDirector
Mar 26, 2026WVEBuy4,954,558$6.06$30.0MDirector
Feb 26, 2026BCAXBuy300,000$16.00$4.8MDirector
Feb 20, 2026ACETBuy74,751$7.27$543K10%+ Owner
Feb 19, 2026ACETBuy74,268$7.21$535K10%+ Owner
Feb 18, 2026ACETBuy74,577$7.04$525K10%+ Owner
Feb 9, 2026SGPBuy248,034$16.00$4.0MDirector
Feb 9, 2026SGPBuy3,441,966$16.00$55.1MDirector
Jan 5, 2026CLYMBuy7,111$3.50$25KDirector
Dec 12, 2025CLYMBuy101,462$2.86$290KDirector

Top Companies Traded

TICKERCOMPANYTRADESTOTAL VOLUME
SIONSionna Therapeutics, Inc.44$21.5M
VORVor Biopharma Inc.43$83.1M
COAGHemab Therapeutics Holdings, Inc.14$53.8M
TYRATyra Biosciences, Inc.6$15.3M
HOWLWerewolf Therapeutics, Inc.6$391K
WVEWave Life Sciences Ltd.5$54.6M
ACETAdicet Bio, Inc.3$1.6M
FULCFulcrum Therapeutics, Inc.3$58.4M
CLYMClimb Bio, Inc.3$780K
MLYSMineralys Therapeutics, Inc.3$38.8M

Other insiders at Sionna Therapeutics, Inc.

6 other tracked filers at SION.