OrbiMed Advisors LLC Insider Trading Activity

Institutional FilerDirector · CIK 1055951

35

Total trades

$82.6M

Total volume

Jul 7, 2026

Last activity

SION

Sionna Therapeutics, Inc.

OrbiMed Advisors LLC, an institutional filer, recorded 31 transactions over the last 12 months across 6 companies totaling $77.5M.

Activity concentrated in SION with 18 filings. The largest single transaction was a sale of SION for $10.5M on Apr 15, 2026.

Performance Scorecard

Forward stock performance after each transaction by OrbiMed Advisors LLC. Buy returns measure price movement after open-market purchases; sell-avoided measures the loss avoided after open-market sales. Success rate counts trades where the insider's direction was right.

PERIODAVG BUY RETURNAVG SELL AVOIDEDSUCCESS RATETRADES
30 days+312.7%-207.9%71%34
90 days+229.6%-269.5%58%31
120 days+404.7%-424.9%74%19

Performance based on stock price movement after each transaction date. Past results do not predict future returns. Not financial advice.

Price & Trades

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Recent Trades

DATETICKERTYPESHARESPRICEVALUEΔ OWNEDROLEFILING
Jul 7, 2026
SIONSell85,918$44.86$3.9M−3.4%Director
May 11, 2026
SIONSell184,639$46.22$8.5M−6.5%Director
May 8, 2026
SIONSell59,767$44.58$2.7M−2.0%Director
May 7, 2026
SIONSell48,546$44.61$2.2M−1.6%Director
Apr 21, 2026
PRLDBuy1,689,189$4.44$7.5M+16.7%Director
Apr 21, 2026
PRLDBuy1,126,126$4.44$5.0MDirector
Apr 18, 2026
SIONSell2,948$44.52$131K−0.1%Director
Apr 17, 2026
SIONSell52,397$44.68$2.3M−1.7%Director
Apr 16, 2026
Filed 8d late
TRAWBuy597,729$1.67$998K+98.7%10%+ Owner
Apr 16, 2026
SIONSell226,906$45.34$10.3M−7.0%Director
Apr 15, 2026
SIONSell235,863$44.64$10.5M−6.8%Director
Apr 14, 2026
SIONSell47,814$44.51$2.1M−1.4%Director
Apr 8, 2026
ACETSell40,416$6.52$264K−100.0%10%+ Owner
Apr 8, 2026
ACETSell32,523$6.29$205K−100.0%10%+ Owner
Apr 7, 2026
ACETSell2,400$6.38$15K−6.9%10%+ Owner
Apr 7, 2026
ACETSell29,319$6.53$191K−45.6%10%+ Owner
Feb 3, 2026
SIONSell29,063$44.58$1.3M−0.8%Director
Feb 2, 2026
SIONSell1,890$44.57$84K−0.1%Director
Dec 24, 2025
Filed 3d late
SIONSell33,356$44.55$1.5M−0.9%Director
Dec 19, 2025
SIONSell875$44.49$39K−0.0%Director
Dec 18, 2025
SIONSell100$44.49$4K−0.0%Director
Dec 17, 2025
SIONSell900$44.50$40K−0.0%Director
Nov 26, 2025
SIONSell1,600$44.49$71K−0.0%Director
Nov 25, 2025
SIONSell11,890$44.60$530K−0.3%Director
Nov 24, 2025
SIONSell94,583$44.54$4.2M−2.6%Director
Oct 23, 2025
PMVPSell1,000,000$1.52$1.5M−16.7%10%+ Owner
Oct 8, 2025
ACETBuy3,500,000$1.00$3.5M+353.4%10%+ Owner
Oct 8, 2025
ACETBuy1,500,000$1.00$1.5M+19.9%10%+ Owner
Sep 10, 2025
PMVPSell500,000$1.80$900K−7.7%10%+ Owner
Aug 25, 2025
Filed 6d late
STTKBuy1,051,021$0.87$912KDirector
Aug 25, 2025
Filed 6d late
STTKBuy5,255,106$0.87$4.6MDirector
Jun 27, 2025
CRVSSell1,176,332$4.16$4.9M−14.1%Director
Jun 26, 2025
PASGSell213,257$0.33$70K−3.4%10%+ Owner
Jun 25, 2025
PASGSell138,800$0.33$46K−2.2%10%+ Owner
Jun 24, 2025
PASGSell231,600$0.35$81K−3.5%10%+ Owner

Top Companies Traded

TICKERCOMPANYTRADESTOTAL VOLUME
SIONSionna Therapeutics, Inc.18$50.4M
ACETAdicet Bio, Inc.6$5.7M
PASGPassage BIO, Inc.3$197K
PRLDPrelude Therapeutics Inc2$12.5M
PMVPPMV Pharmaceuticals, Inc.2$2.4M
STTKShattuck Labs, Inc.2$5.5M
TRAWTraws Pharma, Inc.1$998K
CRVSCorvus Pharmaceuticals, Inc.1$4.9M

Other insiders at Sionna Therapeutics, Inc.

6 other tracked filers at SION.