Opaleye Management Inc. Insider Trading Activity

Institutional Filer10%+ Owner · CIK 1595855

107

Total trades

$33.8M

Total volume

May 21, 2026

Last activity

ACOG

Alpha Cognition Inc.

Opaleye Management Inc., an institutional filer, recorded 103 transactions over the last 12 months across 6 companies totaling $28.2M.

Activity concentrated in ACOG with 30 filings. The largest single transaction was a sale of HROW for $5.3M on Mar 4, 2026.

Performance Scorecard

Forward stock performance after each transaction by Opaleye Management Inc.. Buy returns measure price movement after open-market purchases; sell-avoided measures the loss avoided after open-market sales. Success rate counts trades where the insider's direction was right.

PERIODAVG BUY RETURNAVG SELL AVOIDEDSUCCESS RATETRADES
30 days+17.4%+6.1%76%100
90 days+36.2%+20.5%79%77
120 days+43.9%+4.1%82%55

Performance based on stock price movement after each transaction date. Past results do not predict future returns. Not financial advice.

Price & Trades

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Recent Trades

Showing the 50 most recent of 107 disclosed trades.

DATETICKERTYPESHARESPRICEVALUEROLE
May 21, 2026ACOGBuy15,945$5.70$91K10%+ Owner
May 20, 2026ACOGBuy8,431$5.89$50K10%+ Owner
May 20, 2026SLGLBuy1,563$64.43$101K10%+ Owner
May 18, 2026ACOGBuy17,395$5.69$99K10%+ Owner
May 15, 2026ACOGBuy16,648$5.83$97K10%+ Owner
May 13, 2026SLGLBuy1,937$66.87$130K10%+ Owner
May 12, 2026SLGLBuy1,500$67.98$102K10%+ Owner
May 1, 2026SNWVSell500$16.11$8K10%+ Owner
May 1, 2026SNWVSell10,081$16.11$162K10%+ Owner
Apr 30, 2026SNWVSell1,000$16.15$16K10%+ Owner
Apr 30, 2026SNWVSell24,000$16.15$388K10%+ Owner
Apr 29, 2026SNWVSell23,360$17.25$403K10%+ Owner
Apr 29, 2026SNWVSell1,000$17.25$17K10%+ Owner
Apr 28, 2026SNWVSell2,500$18.47$46K10%+ Owner
Apr 28, 2026SNWVSell43,788$18.47$809K10%+ Owner
Apr 21, 2026SNWVSell202$20.50$4K10%+ Owner
Apr 17, 2026SNWVSell11,267$20.46$231K10%+ Owner
Apr 17, 2026SNWVSell5,000$20.46$102K10%+ Owner
Mar 30, 2026ACOGBuy1,850$4.99$9K10%+ Owner
Mar 27, 2026ACOGBuy10,000$5.08$51K10%+ Owner
Mar 26, 2026ACOGBuy7,319$5.28$39K10%+ Owner
Mar 25, 2026ACOGBuy8,581$5.43$47K10%+ Owner
Mar 24, 2026SLGLBuy5,000$72.00$360K10%+ Owner
Mar 24, 2026SLGLBuy34,665$72.00$2.5M10%+ Owner
Mar 24, 2026ACOGBuy4,182$5.59$23K10%+ Owner
Mar 19, 2026ACOGBuy2,094$5.71$12K10%+ Owner
Mar 18, 2026ACOGBuy2,481$5.75$14K10%+ Owner
Mar 16, 2026ACOGBuy1,331$5.78$8K10%+ Owner
Mar 13, 2026ACOGBuy7,358$5.75$42K10%+ Owner
Mar 12, 2026ACOGBuy5,708$5.85$33K10%+ Owner
Mar 9, 2026ACOGBuy2,179$5.85$13K10%+ Owner
Mar 6, 2026ACOGBuy1,900$5.80$11K10%+ Owner
Mar 5, 2026ACOGBuy42,023$5.80$244K10%+ Owner
Mar 5, 2026ACOGBuy5,000$5.80$29K10%+ Owner
Mar 4, 2026HROWSell4,263$39.67$169K10%+ Owner
Mar 4, 2026HROWSell134,000$39.67$5.3M10%+ Owner
Mar 4, 2026ACOGBuy19,795$5.81$115K10%+ Owner
Mar 3, 2026HROWSell59,000$39.15$2.3M10%+ Owner
Mar 3, 2026ACOGBuy5,000$5.75$29K10%+ Owner
Mar 3, 2026ACOGBuy46,411$5.75$267K10%+ Owner
Mar 3, 2026HROWSell1,309$39.15$51K10%+ Owner
Mar 2, 2026ACOGBuy20,000$5.80$116K10%+ Owner
Feb 27, 2026ACOGBuy3,638$5.99$22K10%+ Owner
Feb 27, 2026HROWSell5,000$54.18$271K10%+ Owner
Feb 26, 2026ACOGBuy590$5.99$4K10%+ Owner
Feb 24, 2026ACOGBuy53,591$5.80$311K10%+ Owner
Feb 24, 2026ACOGBuy5,000$5.80$29K10%+ Owner
Feb 23, 2026ACOGBuy4,181$5.89$25K10%+ Owner
Feb 23, 2026ACOGBuy95,819$5.89$565K10%+ Owner
Feb 20, 2026ACOGBuy2,819$5.84$16K10%+ Owner

Top Companies Traded

TICKERCOMPANYTRADESTOTAL VOLUME
ACOGAlpha Cognition Inc.30$2.5M
SLGLSol-Gel Technologies Ltd.27$7.1M
CDXSCODEXIS, INC.26$11.7M
SNWVSANUWAVE Health, Inc.12$2.2M
HROWHARROW, INC.10$10.3M
ETONEton Pharmaceuticals, Inc.2$125K