Opaleye Management Inc. Insider Trading Activity
Opaleye Management Inc., an institutional filer, recorded 108 transactions over the last 12 months across 6 companies totaling $31.0M.
Activity concentrated in ACOG with 38 filings. The largest single transaction was a sale of HROW for $5.3M on Mar 4, 2026.
Performance Scorecard
Forward stock performance after each transaction by Opaleye Management Inc.. Buy returns measure price movement after open-market purchases; sell-avoided measures the loss avoided after open-market sales. Success rate counts trades where the insider's direction was right.
| PERIOD | AVG BUY RETURN | AVG SELL AVOIDED | SUCCESS RATE | TRADES |
|---|---|---|---|---|
| 30 days | +16.0% | +6.1% | 79% | 121 |
| 90 days | +32.6% | +33.9% | 83% | 107 |
| 120 days | +37.8% | +24.3% | 86% | 107 |
Performance based on stock price movement after each transaction date. Past results do not predict future returns. Not financial advice.
Price & Trades
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Showing the 50 most recent of 126 disclosed trades.
| DATE | TICKER | TYPE | SHARES | PRICE | VALUE | Δ OWNED | ROLE | FILING |
|---|---|---|---|---|---|---|---|---|
Oct 16, 2026 | ACOG | Buy | 14,283 | $8.23 | $118K | +0.4% | 10%+ Owner | |
Oct 15, 2026 | ACOG | Buy | 22,657 | $8.43 | $191K | +0.7% | 10%+ Owner | |
Sep 29, 2026 | GRCE | Buy | 7,849 | $2.09 | $16K | +0.3% | 10%+ Owner | |
Sep 23, 2026 | GRCE | Buy | 5,318 | $2.10 | $11K | +0.2% | 10%+ Owner | |
Sep 21, 2026 | GRCE | Buy | 9,771 | $2.10 | $21K | +0.3% | 10%+ Owner | |
Aug 31, 2026 | SLGL | Buy | 5,000 | $68.23 | $341K | +1.0% | 10%+ Owner | |
Aug 31, 2026 | SLGL | Buy | 217 | $69.10 | $15K | +0.0% | 10%+ Owner | |
Aug 28, 2026 | SLGL | Buy | 10,000 | $71.40 | $714K | +2.1% | 10%+ Owner | |
Aug 28, 2026 | SLGL | Buy | 20,113 | $68.42 | $1.4M | +4.1% | 10%+ Owner | |
Aug 28, 2026 | SLGL | Buy | 5,000 | $68.81 | $344K | +1.0% | 10%+ Owner | |
Aug 14, 2026 Filed 3d late | GRCE | Buy | 11,608 | $2.09 | $24K | +0.4% | 10%+ Owner | |
Aug 3, 2026 | ACOG | Buy | 50,000 | $8.00 | $400K | +1.7% | 10%+ Owner | |
Jul 31, 2026 | ACOG | Buy | 2,900 | $7.92 | $23K | +0.1% | 10%+ Owner | |
Jul 24, 2026 | ACOG | Buy | 130 | $7.90 | $1K | +0.0% | 10%+ Owner | |
Jul 23, 2026 | ACOG | Buy | 49,849 | $7.80 | $389K | +1.7% | 10%+ Owner | |
Jul 22, 2026 | ACOG | Buy | 10,000 | $7.83 | $78K | +11.1% | 10%+ Owner | |
Jul 22, 2026 | ACOG | Buy | 140,237 | $7.83 | $1.1M | +5.0% | 10%+ Owner | |
Jul 14, 2026 | SLGL | Buy | 920 | $73.43 | $68K | +0.2% | 10%+ Owner | |
Jul 13, 2026 | SLGL | Buy | 775 | $73.89 | $57K | +0.2% | 10%+ Owner | |
May 21, 2026 | ACOG | Buy | 15,945 | $5.70 | $91K | +0.6% | 10%+ Owner | |
May 20, 2026 | SLGL | Buy | 1,563 | $64.43 | $101K | +0.3% | 10%+ Owner | |
May 20, 2026 | ACOG | Buy | 8,431 | $5.89 | $50K | +0.3% | 10%+ Owner | |
May 18, 2026 | ACOG | Buy | 17,395 | $5.69 | $99K | +0.7% | 10%+ Owner | |
May 15, 2026 | ACOG | Buy | 16,648 | $5.83 | $97K | +0.7% | 10%+ Owner | |
May 13, 2026 | SLGL | Buy | 1,937 | $66.87 | $130K | +0.4% | 10%+ Owner | |
May 12, 2026 | SLGL | Buy | 1,500 | $67.98 | $102K | +0.3% | 10%+ Owner | |
May 1, 2026 | SNWV | Sell | 500 | $16.11 | $8K | −9.1% | 10%+ Owner | |
May 1, 2026 | SNWV | Sell | 10,081 | $16.11 | $162K | −1.2% | 10%+ Owner | |
Apr 30, 2026 | SNWV | Sell | 1,000 | $16.15 | $16K | −15.4% | 10%+ Owner | |
Apr 30, 2026 | SNWV | Sell | 24,000 | $16.15 | $388K | −2.7% | 10%+ Owner | |
Apr 29, 2026 | SNWV | Sell | 1,000 | $17.25 | $17K | −13.3% | 10%+ Owner | |
Apr 29, 2026 | SNWV | Sell | 23,360 | $17.25 | $403K | −2.6% | 10%+ Owner | |
Apr 28, 2026 | SNWV | Sell | 43,788 | $18.47 | $809K | −4.6% | 10%+ Owner | |
Apr 28, 2026 | SNWV | Sell | 2,500 | $18.47 | $46K | −25.0% | 10%+ Owner | |
Apr 21, 2026 | SNWV | Sell | 202 | $20.50 | $4K | −0.0% | 10%+ Owner | |
Apr 17, 2026 | SNWV | Sell | 11,267 | $20.46 | $231K | −1.2% | 10%+ Owner | |
Apr 17, 2026 | SNWV | Sell | 5,000 | $20.46 | $102K | −33.3% | 10%+ Owner | |
Mar 30, 2026 | ACOG | Buy | 1,850 | $4.99 | $9K | +0.1% | 10%+ Owner | |
Mar 27, 2026 | ACOG | Buy | 10,000 | $5.08 | $51K | +0.4% | 10%+ Owner | |
Mar 26, 2026 | ACOG | Buy | 7,319 | $5.28 | $39K | +0.3% | 10%+ Owner | |
Mar 25, 2026 | ACOG | Buy | 8,581 | $5.43 | $47K | +0.4% | 10%+ Owner | |
Mar 24, 2026 | ACOG | Buy | 4,182 | $5.59 | $23K | +0.2% | 10%+ Owner | |
Mar 24, 2026 | SLGL | Buy | 5,000 | $72.00 | $360K | +50.0% | 10%+ Owner | |
Mar 24, 2026 | SLGL | Buy | 34,665 | $72.00 | $2.5M | +7.7% | 10%+ Owner | |
Mar 19, 2026 | ACOG | Buy | 2,094 | $5.71 | $12K | +0.1% | 10%+ Owner | |
Mar 18, 2026 | ACOG | Buy | 2,481 | $5.75 | $14K | +0.1% | 10%+ Owner | |
Mar 16, 2026 | ACOG | Buy | 1,331 | $5.78 | $8K | +0.1% | 10%+ Owner | |
Mar 13, 2026 | ACOG | Buy | 7,358 | $5.75 | $42K | +0.3% | 10%+ Owner | |
Mar 12, 2026 | ACOG | Buy | 5,708 | $5.85 | $33K | +0.2% | 10%+ Owner | |
Mar 9, 2026 | ACOG | Buy | 2,179 | $5.85 | $13K | +0.1% | 10%+ Owner |