Baker Bros. Advisors LP Insider Trading Activity
Baker Bros. Advisors LP, an institutional filer, recorded 82 transactions over the last 12 months across 6 companies totaling $306.7M.
Activity concentrated in MDGL with 54 filings. The largest single transaction was a purchase of KYMR for $158.1M on Dec 11, 2025.
Performance Scorecard
Forward stock performance after each transaction by Baker Bros. Advisors LP. Buy returns measure price movement after open-market purchases; sell-avoided measures the loss avoided after open-market sales. Success rate counts trades where the insider's direction was right.
| PERIOD | AVG BUY RETURN | AVG SELL AVOIDED | SUCCESS RATE | TRADES |
|---|---|---|---|---|
| 30 days | +16.6% | -2493.0% | 88% | 84 |
| 90 days | +45.2% | -1833.4% | 90% | 84 |
| 120 days | +52.5% | -1783.4% | 93% | 84 |
Performance based on stock price movement after each transaction date. Past results do not predict future returns. Not financial advice.
Price & Trades
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Showing the 50 most recent of 84 disclosed trades.
| DATE | TICKER | TYPE | SHARES | PRICE | VALUE | Δ OWNED | ROLE | FILING |
|---|---|---|---|---|---|---|---|---|
Dec 18, 2025 | KOD | Buy | 217,428 | $23.00 | $5.0M | +16.2% | Director | |
Dec 18, 2025 | KOD | Buy | 2,391,268 | $23.00 | $55.0M | +15.0% | Director | |
Dec 11, 2025 | KYMR | Buy | 167,192 | $86.00 | $14.4M | +31.3% | Director | |
Dec 11, 2025 | KYMR | Buy | 1,838,621 | $86.00 | $158.1M | +30.1% | Director | |
Nov 20, 2025 | TRDA | Buy | 1,186 | $9.07 | $11K | +0.3% | 10%+ Owner | |
Nov 20, 2025 | TRDA | Buy | 1,213 | $9.07 | $11K | +0.3% | 10%+ Owner | |
Nov 20, 2025 | TRDA | Buy | 13,386 | $9.07 | $121K | +0.3% | 10%+ Owner | |
Nov 20, 2025 | TRDA | Buy | 13,082 | $9.07 | $119K | +0.3% | 10%+ Owner | |
Nov 12, 2025 | TRDA | Buy | 11,494 | $7.95 | $91K | +0.2% | 10%+ Owner | |
Nov 12, 2025 | TRDA | Buy | 1,040 | $7.95 | $8K | +0.3% | 10%+ Owner | |
Nov 12, 2025 | TRDA | Buy | 80,881 | $7.73 | $625K | +1.8% | 10%+ Owner | |
Nov 12, 2025 | TRDA | Buy | 7,321 | $7.73 | $57K | +2.0% | 10%+ Owner | |
Nov 11, 2025 | TRDA | Buy | 2,795 | $7.54 | $21K | +0.8% | 10%+ Owner | |
Nov 11, 2025 | TRDA | Buy | 1,059 | $7.39 | $8K | +0.3% | 10%+ Owner | |
Nov 11, 2025 | TRDA | Buy | 11,701 | $7.39 | $86K | +0.3% | 10%+ Owner | |
Nov 11, 2025 | TRDA | Buy | 30,879 | $7.54 | $233K | +0.7% | 10%+ Owner | |
Nov 10, 2025 | TRDA | Buy | 2,947 | $7.22 | $21K | +0.1% | 10%+ Owner | |
Nov 10, 2025 | TRDA | Buy | 267 | $7.22 | $2K | +0.1% | 10%+ Owner | |
Nov 10, 2025 | TRDA | Buy | 25,364 | $7.21 | $183K | +0.6% | 10%+ Owner | |
Nov 10, 2025 | TRDA | Buy | 2,296 | $7.21 | $17K | +0.6% | 10%+ Owner | |
Oct 1, 2025 | KALA | Sell | 50,640 | $1.38 | $70K | −52.1% | Other | |
Oct 1, 2025 | KALA | Sell | 462,967 | $1.38 | $641K | −52.1% | Other | |
Sep 30, 2025 | KALA | Sell | 21,376 | $1.60 | $34K | −18.0% | Other | |
Sep 30, 2025 | KALA | Sell | 195,425 | $1.60 | $312K | −18.0% | Other | |
Sep 8, 2025 | CELC | Buy | 4,212 | $58.02 | $244K | +0.1% | 10%+ Owner | |
Sep 8, 2025 | CELC | Buy | 13,976 | $56.22 | $786K | +2.0% | 10%+ Owner | |
Sep 8, 2025 | CELC | Buy | 151,524 | $56.22 | $8.5M | +2.1% | 10%+ Owner | |
Sep 8, 2025 | CELC | Buy | 388 | $58.02 | $23K | +0.1% | 10%+ Owner | |
Aug 20, 2025 | MDGL | Buy | 1,919 | $380.78 | $731K | +0.1% | Director | |
Aug 20, 2025 | MDGL | Buy | 480 | $380.44 | $183K | +0.2% | Director | |
Aug 20, 2025 | MDGL | Buy | 5,209 | $380.44 | $2.0M | +0.3% | Director | |
Aug 20, 2025 | MDGL | Buy | 176 | $380.78 | $67K | +0.1% | Director | |
Aug 20, 2025 | MDGL | Buy | 873 | $381.12 | $333K | +0.4% | Director | |
Aug 20, 2025 | MDGL | Buy | 9,477 | $381.12 | $3.6M | +0.5% | Director | |
Aug 20, 2025 | MDGL | Buy | 105 | $382.29 | $40K | +0.1% | Director | |
Aug 20, 2025 | MDGL | Buy | 1,136 | $382.29 | $434K | +0.1% | Director | |
Aug 20, 2025 | MDGL | Buy | 262 | $382.82 | $100K | +0.1% | Director | |
Aug 20, 2025 | MDGL | Buy | 2,838 | $382.82 | $1.1M | +0.1% | Director | |
Aug 20, 2025 | MDGL | Buy | 373 | $383.79 | $143K | +0.2% | Director | |
Aug 20, 2025 | MDGL | Buy | 4,049 | $383.79 | $1.6M | +0.2% | Director | |
Aug 20, 2025 | MDGL | Buy | 1,248 | $385.06 | $481K | +0.6% | Director | |
Aug 20, 2025 | MDGL | Buy | 13,545 | $385.06 | $5.2M | +0.7% | Director | |
Aug 20, 2025 | MDGL | Buy | 409 | $387.07 | $158K | +0.2% | Director | |
Aug 20, 2025 | MDGL | Buy | 4,441 | $387.07 | $1.7M | +0.2% | Director | |
Aug 20, 2025 | MDGL | Buy | 34 | $389.00 | $13K | +0.0% | Director | |
Aug 20, 2025 | MDGL | Buy | 366 | $389.00 | $142K | +0.0% | Director | |
Aug 20, 2025 | MDGL | Buy | 231 | $389.89 | $90K | +0.1% | Director | |
Aug 20, 2025 | MDGL | Buy | 2,506 | $389.89 | $977K | +0.1% | Director | |
Aug 20, 2025 | MDGL | Buy | 862 | $392.24 | $338K | +0.4% | Director | |
Aug 20, 2025 | MDGL | Buy | 9,362 | $392.24 | $3.7M | +0.5% | Director |
Top Companies Traded
Other insiders at MADRIGAL PHARMACEUTICALS, INC.
8 other tracked filers at MDGL.